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B-SELFIE DEEP DNA-RNA | Bios Beauty

Ultra-intensive facial treatment based on PDNR, the latest frontier in cell regeneration

We firmly believe in the effectiveness of our formulations and know that you will love them as much as we do. If for some reason you are not 100% satisfied with our products, we will give you a full refund as long as the goods are returned to us within 30 days of the delivery of your order.

The first ultra-intensive treatment harnessing the unparalleled power of PDNR + RNA complex for the most amazing facial regeneration.

Tired and asphyxiated skin will be just a memory, giving way to new, youthful and radiant skin.

  •  PDRN stimulates cell regeneration and the DNA synthesis process for powerful anti-ageing and anti-oxidant action
  •  SODIUM DNA with healing properties protects against damage to the immune system, photo-oxidation and slows down ageing 
  • Soluble collagen, a fundamental protein of the dermis, and hyaluronic acid prevent and combat skin withering and laxity 
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B-SELFIE DEEP DNA-RNA: the effectiveness of deep stimulation

B-SELFIE DEEP DNA-RNA: the effectiveness of deep stimulation

The micro-injective ability of the B-SELFIE DEEP applicator releases a powerful synergy between regenerating and anti-age substances, and the enhancement of the physiological process of skin repair, a consequence of the controlled damage generated by the microneedles of the device.  

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B-SELFIE DEEP DNA RNA can easily and painlessly deliver functional substances, highly available, near the stratum germinativum where new epidermal cells are born.

Why does it work?

Why does it work?

B-SELFIE DEEP DNA RNA thanks to the patented system of administration of its incredible regenerating serum, allows an absorption of active substances 30 times more effective than a traditional cosmetic topical application.  

B-SELFIE DEEP DNA-RNA: regenerated face thanks to the acceleration of cell turnover

B-SELFIE DEEP DNA-RNA: regenerated face thanks to the acceleration of cell turnover

A completely regenerated skin

PDRN is a mixture of deoxyribonucleotides effective in promoting cell turnover: cells regenerate faster by rising from the basal layer to the surface layer, renewing. PDNR also increases collagen synthesis and promotes the processes of repair and healing of the skin, also performing an important anti-aging action.

Powerful remodeling anti-age 

Powerful remodeling anti-age 

Copper Tripeptide-1 is a peptide that helps reshape tissues, prevent wrinkles and reduce their depth. It also promotes skin renewal, increases skin elasticity and reverses aging processes. 

Say goodbye to enlarged pores for a brighter and more uniform skin

Say goodbye to enlarged pores for a brighter and more uniform skin

The ability of PDRN to stimulate the synthesis of new DNA (new epidermal cells) renews the stratum corneum freeing the skin from imperfection and thickening minimizing enlarged pores.

Thanks to its crystalline structure, Calcium Sodium Borosilicate reflects light evenly, creating a luminous effect on the skin.

Compact, toned and elastic skin

Compact, toned and elastic skin

The synergy between Biopeptides, Peptides and Amino Acids promotes skin elasticity, tone and firmness of tissues, reduces and prevents the formation of expression lines by stimulating the production of collagen, elastin and hyaluronic acid. 

These active ingredients, in synergy with Soluble Collagen, which has elasticizing properties, exert an important action and toning.

Hydrated and plumped skin 

Hydrated and plumped skin 

Sonicated Hyaluronic Acid for a corrective and deep anti-age action.

Hyaluronic acid with high molecular weight for a film-forming, silky and moisturizing effect  

Pseudoalteromonas Ferment Extract, meets the mix of amino acids (Proline, Alanine and Glycine), creating a high-definition molecular film that improves the appearance of the skin by restoring the correct levels of skin hydration. 

RNA Complex regenerates and protects the skin from damage related to photo-aging

RNA Complex regenerates and protects the skin from damage related to photo-aging

The RNA-based complex has a new concept of photoprotection, that is, it protects against premature skin aging and the damage to the immune system of the skin caused by exposure to UV rays. 

The action combined with Thioctic Acid and Coenzyme Q10, promote the regeneration of skin cells protecting them from damage caused by UV rays, pollution, toxins and oxidative stress, reducing wrinkles and making the skin more compact and elastic.

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When can you see visible results?

When can you see results?

Already during the treatment there is a marked improvement in the texture and tone of the skin as well as the increase in the brightness of the face and the reduction of wrinkles, but the result will continue to improve in the five days following treatment and will be maintained for an entire cell cycle. For a correct epidermal regeneration protocol, we recommend to carry out an intraepidermal treatment every 21 days.

How to use

The watchword is delicacy.

How to use

Clean and disinfect the face and neck, remove the sterile head from the package and screw it on the syringe.

Place the syringe vertically on the skin by lightly pressing the plunger to inject the serum directly into the epidermis.

Follow the traction lines in the operating instructions.

Warning: to properly perform the treatment in total safety you must know that there are 4 areas of the face where you will not have to inject the product, but simply facilitate the passage into the epidermis. You will find everything indicated on the package leaflet that you will receive together with the product.

At the end of the application of the product, with clean and disinfected hands, massage until complete absorption of the excess serum. 

Close the treatment by applying the soothing mask and leave it on for 20 minutes.

For further clarification, or if you have any questions after purchase contact us: our Beauty Specialist will be available to help you with any need.

Doctor’s advice

Doctor's Advice

What does the Aesthetic Physician say?

Here is the opinion of Doctor Andrea Piccardi:

"The use of DEEP DNA RNA technology for the administration of regenerating serum right near the stratum germinativum allows functional substances to stimulate and support cell regeneration: the process of cell ascension from the stratum germinativum up to the epidermal layer is accelerated. The antioxidant and protective factors present in the formula are powerful allies in the fight against aging.

Personally, in order to consolidate the regenerative effects of treatment, I would recommend to repeat the treatment two or three times with an interval of 21 days which corresponds approximately to the time necessary for a complete cell turnover.

I carried out some treatments on elderly female patients, and the results were particularly satisfactory as a better adhesion of the skin to the mandibular profile and a better elasticity and a firmness, perceptible even to the touch. Hydration and luminosity as well as improved skin texture, were the first to manifest immediately after treatment."

B-SELFIE DEEP DNA-RNA| Bios Beauty

  1. €139.00
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FAQ

INGREDIENTS: AQUA, GLYCERIN, PVP, SODIUM POLYACRYLOYLDIMETHYL TAURATE, SODIUM HYALURONATE, DISODIUM EDTA, ARGININE, PSEUDOALTEROMONAS FERMENT EXTRACT, LECITHIN, SORBITOL, MANNITOL, DISODIUM ADENOSINE TRIPHOSPHATE, RNA, PYRIDOXINE HCL, XANTHAN GUM, SOLUBLE COLLAGEN, CALCIUM SODIUM BOROSILICATE, CAPRYLYL GLYCOL, HISTIDINE HCL, THIOCTIC ACID, ETHYLHEXYLGLYCERIN, PHENYLALANINE, CAPRYLIC/CAPRIC TRIGLYCERIDE, UBIQUINONE, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, TYROSINE, SODIUM DNA, ALANINE, PROLINE, SERINE, COPPER TRIPEPTIDE-1, SH-POLYPEPTIDE-11, SH-POLYPEPTIDE-1, SODIUM PHOSPHATE, PHENOXYETHANOL, IMIDAZOLIDINYL UREA, CI 47005, GLYCERYL CAPRYLATE, SODIUM HYDROXIDE, SODIUM OLEATE, GLYCINE SOJA OIL, HYDROGENATED LECITHIN, SILVER OXIDE.

B-SELFIE DEEP DNA RNA Bios Beauty is the first ultra-intensive treatment that takes advantage of the unparalleled power of PDNR + RNA complex for the most amazing facial regeneration. The tired and asphyxiated skin will be just a memory giving way to a new skin, young and bright. B-SELFIE DEEP DNA RNA Bios Beauty is the first professional DIY regenerating intraepidermal treatment that, thanks to a new injective technology completely painless, is able to administer an extraordinary regenerating cocktail in the epidermis.

B-SELFIE DEEP DNA RNA Bios Beauty uses a pre-dosed syringe with controlled release, equipped with 19 injective microneedles 0.5 mm, which allows you to carry out a professional treatment do-it-yourself in complete safety and pain free.

The functional substances present in the formulation of B-SELFIE DEEP DNA RNA Bios Beauty have specific properties aimed at achieving tangible anti-age results, thus promoting the achievement of a younger face, relaxed, bright.

  • Yes, B-SELFIE DEEP DNA RNA Bios Beauty is easy to use.

    The watchword is delicacy.


    • Clean and disinfect the skin of the face and neck, and extract the sterile head from the package and screw it on the syringe.
    • Remove the cap on the head that protects the micro-needles and press the plunger of the syringe until you see the serum coming out of the needles.
    • Gently and vertically place the syringe on the skin with gentle pressure and press the plunger gently without reaching the bottom to avoid injecting too much serum as it is not recommended.
    • Repeat on the areas indicated in the package leaflet.
    • When you are done with the first syringe, screw the head on the second syringe and continue the treatment insisting on the critical areas (nasolabial folds, bar code of the upper lip, wrinkles of the puppet (angle of the mouth and angle of the chin)glabellar wrinkles, mandibular profile and neck wrinkles).
    • At the end of the serum infiltration, with clean and disinfected hands, make a circular massage starting from the center of the face and going upwards, until complete absorption of excess serum on the skin. 
    • Close the treatment by applying the soothing mask and leave it on for 20 minutes.

B-SELFIE DEEP DNA RNA Bios Beauty is completely painless. The absence of pain results from the fact that microneedles of the length of 0.5 mm can not exceed the dermobasal stratum and therefore do not reach the pain receptors. In order to avoid pain, we recommend that you perform the treatment with the utmost delicacy.

Of course, if you have any questions or doubts about how to carry out the treatment you can contact us directly. Our Beauty Specialist will be at your disposal to follow you step by step during the application.

B-SELFIE DEEP DNA RNA Bios Beauty has been subjected to rigorous tests both at the design and production stages such as patch testing, microbiological testing and dermatological testing.

We also inform you that B-SELFIE DEEP DNA RNA Bios Beauty has been produced in compliance with REGULATION (EC) No 1223/2009 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 30 November 2009 on cosmetic products and complies with good manufacturing practice (GMP/ISO 22716) published in the Official Journal of the European Union. In addition, the product was successfully notified through the European CPNP portal. The sterile applicator with micro-needles for intraepidermal application is classified as a Medical device class IIa and has also been manufactured in compliance with European standards.

In a package of B-SELFIE DEEP DNA RNA there are: 2 predosed  and disposable 5 ml syringes, 1 sterile applicator with micro-needles 0.5 mm length for intraepidermal delivery, and 1 spout applicator for topical application.

NO: For the first 24 hours avoid the application of make-up products, especially foundation and powder products. The intraepidermal application through the micro-needles present on the sterile head is a minimally invasive procedure that induces controlled lesions that trigger a skin response, characterized by the release of growth factors that lead to the synthesis of a new tissue rich in collagen. After treatment with B-SELFIE DEEP DNA RNA, presenting the skin of microlesions caused by repeated puncture of micro-needles, it is not recommended to apply any make-up productup as micro-holes would be clogged by such substances and infections could occur. It’s important that the skin breathes and regenerates properly until fully healed.

NO: Skincare products such as creams or serums other than B-SELFIE products are not recommended because not knowing the formulation could interact negatively.

The treatment is consolidated after 5 days from the first application and is kept for several weeks depending on the type of skin, its state and its hydration. To keep the skin in good condition, about the tone, elasticity, hydration and brightness, repeat the treatment every 21 days.

A single intraepidermal B-SELFIE DEEP DNA RNA treatment involves using both syringes at once. The amount of serum contained in the two syringes is sufficient to treat the face, neck and décolleté areas in a complete manner. Once the contents of the first syringe are exhausted, the applicator with micro-needles must be mounted immediately on the other syringe to continue treatment. 

If properly carried out treatment, then should not advance the product. In the event that the product is left over, and you want to use it later, in the package in addition to the applicator with micro-needles, there is a nozzle applicator for topical application. It is contraindicated to reuse the head with micro-needles in moments after treatment, as it would no longer be sterile and could be a vehicle of bacteria and cause infections.  

The topical spout applicator is definitely the safest option. Moreover, the passage of the active ingredients in the epidermis is guaranteed by the high molecular weight hyaluronic acid that acts as a carrier of the active substances.

NO. The safety of the final formulation, ingredients or combinations of ingredients used in B-SELFIE DEEP DNA RNA is ensured through alternative methods that do not involve the use of animals to conduct the tests. 

It is good to know that the treatment of acne in the active phase is a medical competence and that it is possible to carry out both medical and aesthetic treatments during the course of prevention, during drug treatment and in the post-acne phase. Depending on the present acneic relevance, with the help of your doctor you can determine whether to proceed to treatment with B-SELFIE DEEP DNA RNA.

As a general guideline, in cases where acne is in an active inflammatory phase with the presence of papules, pustules and cysts, it is not recommended to carry out treatment with B-SELFIE DEEP DNA RNA, as the treatment with intraepidermal vehicle requires the use of an applicator with micro-needles, which although sterile, could still be a source of infection transmission and further worsen the inflammatory state of the skin.

In cases of acne no longer active, in which you are only in the presence of post-acne scars, B-treatmentSELFIE DEEP DNA RNA is even indicated as it has an action to improve the homogeneity of the complexion and the filling of scar depressions.

However, we recommend that you consult your doctor.

B-SELFIE DEEP DNA RNA is a safe product that contains no irritants. In the case of particularly sensitive skin it is possible to witness a temporary redness a little more persistent due to the use of the applicator with micro-needles. In this case, we recommend applying at the end of the treatment and the next day the B-SELFIE INFINITY mask with a strong emollient and soothing action.

It is good to know that the treatment of dermatitis is of medical competence. As a general guideline, if you are in the presence of dermatitis in the active or acute phase, we recommend that you contact your doctor to evaluate whether to proceed to treatment with B-SELFIE DEEP DNA RNA. In the presence of inactive dermatitis we found no side effects. High molecular weight hyaluronic acid, cross-linked hyaluronic acid, the cocktail of vitamins and amino acids contained within the formula, have moisturizing and regenerating properties that can bring benefit in these cases. A medical evaluation is however essential in these cases.

The topical application with plastic spout inside the package, however, has no contraindications.

The serum contained in the two predosed syringes does not contain nickel. The composition of the micro-needles that allow the penetration of the serum into the epidermis, has in itself a very small percentage of nickel; the same percentage contained in all the needles used in medicine internationally for sampling and administration. In addition, the micro-needle head being sterilized and hermetically sealed, any contamination with the other components inside the package is excluded.

B-SELFIE DEEP DNA RNA head micro-needles are of SUS 304 stainless steel. This material is commonly used in the medical field for the manufacture of surgical instruments and test instruments, as well as in orthopedics, orthodontics and dentistry, because of its corrosion resistance, its correct bio-behavior and a favorable bio-affinity. Among the components of SUS 304 stainless steel are activated carbon, amorphous silicon powder, colloidal manganese, phosphorus, sulfur, nickel element, nitrogen, chromium and iron. The micro-needles were subjected to several tests to assess their safety, including the cytotoxicity test based on the agar diffusion methodology which found that there is no toxic effect. The quantity of potentially toxic ions released is well below the maximum quantities declared within safe limits and the threshold value normally absorbed by the daily diet; Therefore, micro-needles do not pose a threat to health nor have a negative effect on the tissues of the face.

The main and best known function of hyaluronic acid is to bind to itself a huge number of water molecules. In cosmetics, hyaluronic acid is generally used in a concentration range between 0.1 and 2%, solubilizing it in the aqueous phase, even at high temperatures. Concentrations higher than 2% give the system a viscosity that makes it difficult to escape from the bottle and the micro-needles on the sterile head. It is erroneously thought that high concentrations of this active substance are synonymous with greater effectiveness, however they would give the product a consistency not suitable for the delivery of the product.

In B-SELFIE DEEP DNA RNA the concentration of hyaluronic acid is also supported by other active ingredients, such as Soluble Collagen, while other ingredients are concerned with nourishing the skin and producing a lifting action, antioxidant, illuminating and stain-resistant such as EGF or Epidermal Growth Factors (Sh polypeptide-11, Sh polypeptide-1), Copper Tripeptide-1, and a Cocktail of Amino Acids (Alanine, Proline, Glycine).

NO: The intraepidermal treatment B-SELFIE DEEP DNA RNA is not indicated for the periocular area as the skin is very delicate and thin, and the length of the micro-needles is not suitable for that area of application. Otherwise, it is recommended to apply topically through the plastic spout inside the package.

NO: It is good to know that our epidermis has different thickness and different characteristics depending on the different areas of the body. Then use B-SELFIE DEEP DNA RNA by conveying the product through the head with micro-needles in parts of the body other than face, neck and décolleté, may be unsuitable or even harmful. The B-SELFIE DEEP DNA RNA intraepidermal treatment has been specially developed to treat specific areas of the face, neck and décolleté.

B-SELFIE DEEP DNA RNA intraepidermal treatment should not be performed in case of infectious skin diseases, uncontrolled diabetes complications, severe and uncontrolled diseases, metal allergies, in case of keloids or hypertrophic scars, in the presence of couperose, inflammation, cysts, skin growths, wounds, acute dermatitis and eczema.

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